Predicting essential proteins by integrating network topology, subcellular localization information, gene expression profile and go annotation data
W Zhang, J Xu, X Zou - IEEE/ACM transactions on …, 2019 - ieeexplore.ieee.org
… Taken together, our new proposed method TEGS perform well in identifying essential
proteins from PPI network, especially when the select top number is relative large. …
proteins from PPI network, especially when the select top number is relative large. …
Network-based methods for predicting essential genes or proteins: a survey
… network topological and biological properties. In Dynamic … provide a more comprehensive
gene expression profile. More … Accordingly, identifying the domains that occur within proteins …
gene expression profile. More … Accordingly, identifying the domains that occur within proteins …
[HTML][HTML] A novel essential protein identification method based on PPI networks and gene expression data
J Zhong, C Tang, W Peng, M Xie, Y Sun, Q Tang… - BMC …, 2021 - Springer
… methods for identifying essential proteins have better results by using biological information.
… characterize the probability of two proteins being in a cluster from a topology perspective (2) …
… characterize the probability of two proteins being in a cluster from a topology perspective (2) …
[HTML][HTML] A novel method for identifying essential genes by fusing dynamic protein–protein interactive networks
F Zhang, W Peng, Y Yang, W Dai, J Song - Genes, 2019 - mdpi.com
… to detect essential genes based on the static protein–protein interactive (… detected essential
genes based on the network topology, gene expression data, and gene ontology information…
genes based on the network topology, gene expression data, and gene ontology information…
Random walk based method to identify essential proteins by integrating network topology and biological characteristics
… methods which have been used for essential protein detection. However, it is still a big …
method applies network topology (ECC), gene expression data (PCC) and GO annotation data (…
method applies network topology (ECC), gene expression data (PCC) and GO annotation data (…
A deep learning framework for gene ontology annotations with sequence-and network-based information
… biological problems and network topological features are very important in the study …
identifying essential proteins based on proteinprotein interaction network and gene expression data…
identifying essential proteins based on proteinprotein interaction network and gene expression data…
Determining protein–protein functional associations by functional rules based on gene ontology and KEGG pathway
… gene expression profiling data [15] or cellular co-localization … that a lot of features were
essential for majority datasets. These … : 0006412 is definitely an effective parameter for identifying …
essential for majority datasets. These … : 0006412 is definitely an effective parameter for identifying …
An integrated systems biology and network-based approaches to identify novel biomarkers in breast cancer cell lines using gene expression data
A Khan, Z Rehman, HF Hashmi, AA Khan… - Interdisciplinary …, 2020 - Springer
… Protein–protein interaction network is a very important … the data set of microarray gene
expression and identifying … of PPI and TF network assessment as a powerful structure for gaining …
expression and identifying … of PPI and TF network assessment as a powerful structure for gaining …
Computational methods for identifying the critical nodes in biological networks
X Liu, Z Hong, J Liu, Y Lin… - Briefings in …, 2020 - academic.oup.com
… new essential proteins based on network topology. CEPPK detects new essential proteins by
integrating network … the gene expression data with the static PPI network to build a dynamic …
integrating network … the gene expression data with the static PPI network to build a dynamic …
[HTML][HTML] Deep GONet: self-explainable deep neural network based on Gene Ontology for phenotype prediction from gene expression data
V Bourgeais, F Zehraoui, M Ben Hamdoune… - BMC …, 2021 - Springer
… by identifying the most important neurons and … based on a MLP constrained by the GO
structure. The constraints are introduced into the network using an adaptive regularization term…
structure. The constraints are introduced into the network using an adaptive regularization term…